"Refeeding starved rats a fat-free diet over a 48 hr period
brings about a marked elevation
in the activity of the enzymes in liver cytoplasm
which catalyze the synthesis of saturated fatty acids
from acetyl CoA and malonyl CoA.
Acetate incorporation into palmitoleic and oleic acid
is also accelerated during this period.
Enhanced capability for the synthesis of these fatty acids
is reflected in
the net accumulation of saturated and monounsaturated fatty acids,
as well as the triglyceride fraction of the liver lipids.
Coincident with these events
the relative amount of linoleic acid among liver fatty acids rapidly falls.
These changes are substantially the same
as those observed in early linoleic acid deficiency."
(emphasis mine)
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